| ZHAO Cun,DONG Taiji,GAO Bingkun,LIU Xu,ZHANG Zihua.Particle motion trajectory tracking based on fiber optic tweezers[J].Optoelectronics Letters,2023,(8):462-467 |
| Particle motion trajectory tracking based on fiber optic tweezers |
| Author Name | Affiliation | | ZHAO Cun | Department of Electrical Information Engineering, Northeast Petroleum University Qinhuangdao Campus, Qinhuangdao 066004, China | | DONG Taiji | College of Electrical and Information Engineering, Northeast Petroleum University, Daqing 163318, China | | GAO Bingkun | College of Electrical and Information Engineering, Northeast Petroleum University, Daqing 163318, China | | LIU Xu | College of Electrical and Information Engineering, Northeast Petroleum University, Daqing 163318, China | | ZHANG Zihua | Faculty of Materials and Manufacturing, Beijing University of Technology, Beijing 100124, China |
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| Abstract: |
| A biosensor based on single-fiber optical tweezers is proposed, which can detect the motion trajectory of cells based on the stable capture and transmission of silica microspheres as well as biological yeast cells by using a tapered optical fiber as a sensing element. The interference cavity is formed by using the fiber tip and the target particle, the detected interference signal is demodulated using Hilbert transform, and the displacement curve of the particle is plotted to realize the particle motion trajectory tracking. This method provides potential technical support for process monitoring of targeted drug delivery in biomedicine. |
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